Games on both Friday and Monday evening this week
The SSE Airtricity League pace-setters Cork City and Dundalk have both gotten off to flying starts, picking up wins from their opening two games of the season.
They're joined at the top of the table by high-flying Bray Wanderers on six points, with surprise package Drogheda United also in the mix.
At the foot of the table, Bohemians, Galway United and Sligo Rovers all go in search of their first points of the season.
Keith Long's side will welcome the Seagulls to Dalymount Park this weekend, while Galway United will make to trip to Finn Park to take on Finn Harps.
Last year's Premier Division champions Dundalk will take on last year's runaway First Division champions Limerick FC at Oriel Park.
Former Dundalk defender Andy Boyle this week made his debut for Preston North End during a 1-1 draw away to Derby County.
Sligo Rovers and St. Patrick's Athletic will both look for their first points of the season when the face off at The Showgrounds.
There's a top of the table clash in Cork City and Drogheda United at United Park. John Caulfield's side will look to maintain their impressive league performances and last season's FAI Cup champions are yet to concede a league goal this term.
Elsewhere, Stephen Bradley's Shamrock Rovers side will aim to build on last week's 2-1 win over Bohemians in the Dublin derby when they welcome Derry City to Tallaght Stadium. Bradley welcomed Robbie Keane to the club this week, as Ireland's record goalscorer trained with the club.
Speaking on this week's Off The Ball, Stuart Byrne admitted he was impressed by the early signs for Bray Wanderers at the start of the 2017 season.
You can catch up with all this week's action from the League of Ireland in this week's Newstalk's SSE Airtricity League Podcast with Oisin Langan and Daniel Kelly.
Bohemians v Bray Wanderers, Dalymount Park (7.45pm)
Dundalk v Limerick, Oriel Park (7.45pm)
Sligo Rovers v St. Patrick's Athletic, The Showgrounds (7.45pm)
Drogheda United v Cork City, United Park (8pm)
Finn Harps v Galway United, Finn Park (8pm)
Shamrock Rovers v Derry City, Tallaght Stadium (8pm)
Galway United v Shamrock Rovers, Eamonn Deacy Park (7pm)
Bray Wanderers v Drogheda United, Carlisle Grounds (7.45pm)
Cork City v Sligo Rovers, Turner's Cross (7.45pm)
Derry City v Dundalk, Maginn Park (7.45pm)
Limerick v Bohemians, Market's Field (7.45pm)
St. Patrick's Athletic v Finn Harps, Richmond Park (7.45pm)
Athlone Town v Longford Town, Athlone Town Stadium (7.45pm)
Cabinteely v Wexford FC, Stradbrook (7.45pm)
U.C.D. v Waterford FC, UCD Bowl (7.45pm)
Cobh Ramblers v Shelbourne, St. Colman's Park (Saturday 11/3, 4pm)
Jonah Ayunga (Sligo Rovers)
Jack Tuite (Shelbourne)
First Team Competitive as and from Monday 6th March
Graham Burke (Shamrock Rovers) - Two Matches, additional red card suspension
Darren Dennehy (St. Patrick's Athletic) - Two Matches, additional red card suspension
Aidan Keena (St. Patrick's Athletic) - Two Matches, additional red card suspension
Republic of Ireland manager Martin O'Neill and Assistant Manager Roy Keane alongside Fulfil co-founders Niall McGrath and Tom Gannon. Irish Brand Fulfil have just announced a three-year exclusive sponsorship deal as they become Official Snack Partners of the FAI.
Fulfil will invest in a passing skills machine used by teams including Barcelona, Liverpool and Manchester United, which will be loaned to clubs nationwide and will also be used on match-days at the Aviva Stadium.