The sides will meet on Thursday June 1
Martin O'Neill will take his team Stateside this summer as they face Mexico in an international friendly in New Jersey.
The sides will meet in the MetLife Stadium on Thursday, June 1 this summer, before they face into a home friendly against Uruguay on June 4.
O'Neill will use their South American opponents as preparation for their 2018 World Cup Qualifier against Austria on June 11 at the Aviva Stadium.
"This is a brilliant match for us in our preparation for our World Cup qualifier against Austria," O'Neill said in a statement released by the FAI on Tuesday afternoon.
"Mexico in the United States couldn't be much tougher but it's exactly what we want. We have another game against Uruguay a few days later at the Aviva Stadium before the Austria game the following week.
"The players who may not have played for a while after their club season has ended will, I'm sure, relish the opportunity to play against such quality opposition."
Ireland have never beaten Mexico in four meetings with the side - drawing three times and losing once. Mexico are currently placed 17th in the FIFA World Rankings.
World Cup USA 94 - Group E - Ireland v Mexico - Citrus Bowl, Orlando. Carlos Hermosillo of Mexico is tackled by Ireland's Phil Babb. Image: Neal Simpson EMPICS Sport