The 17-14 loss drops the Panthers to 1-4 for the season
Roberto Aguayo scored a field-goal with the last kick of the game to help the Tampa Bay Buccaneers to a 17-14 win away to the Carolina Panthers.
The win moves Tampa Bay to 2-3, while the Panthers who won the first 14 games of last season, are now 1-4 this season.
The Panthers began the game without MVP Cam Newton, who was missing the game due to concussion. Derek Anderson, who has not started a game since the 2014 season, replaced Newton.
The 33-year-old, who is in his thirteenth season in the NFL, threw two interceptions and no touchdown passes in the game. Despite the interceptions, Anderson still threw for 278 yards, which was 59 more than Tampa Bay's quarterback Jameis Winston.
Carolina's Cameron Artis-Payne scored the team's two touchdowns, as Mike Evans scored Tampa's only six-pointer. The Tampa touchdown was also converted for two points.
After five games, Carolina now lie bottom of the NFC South, with Tampa Bay in second place, behind the Atlanta Falcons.