The Scot said they had "mutually agreed" to end their partnership
World number three Andy Murray has split from coach Amelie Mauresmo after two years.
Murray thanked the two-time Grand Slam winner for her time working with him, but said the pair had "mutually agreed" to end their professional relationship.
"I've learned a lot from Amelie over the last two years, bot on and off the court" he said in a statement.
"I'll take some time to consider the next steps and how we progress from here, but I'd like to thank her for everything she has done. She's been an invaluable member of the team.
"She's been a calming influence in the team and we will all miss having her around."
Mauresmo was absent for Murray's Madrid Open final defeat to Novak Djokovic, with Jamie Delgado in the coaching role.
Andy Murray gestures after losing a point to Novak Djokovic during their Madrid Open tennis tournament final match in Madrid yesterday. Djokovic won 6-2, 3-6 and 6-3. (AP Photo/Francisco Seco)
The pair began working together before Wimbledon in 2014 when Murray failed to defend his title.
He has failed to add to his two Grand Slam titles since splitting with Ivan Lendl.
"Working with Andy over the last two years has been a fantastic experience for me" she said.
"I’ve thoroughly enjoyed being part of the great team of people he has around him. Dedicating enough time along with the travel has been a challenge for me. I wish him and team well and I hope he goes on to win many more titles."