Ryan is one of two changes from the side that defeated Stade Francais last week
Anthony Foley has named his side for Sunday's Champions Cup encounter against Treviso making two changes to the side defeated Stade Francais last week.
For Munster's 150th European Cup game the Ryan duo of John and Donnacha are introduced in the pack with John named at tight-head and Donncha in the second row.
Munster's seven representatives that were included in Ireland's Six Nations squad earlier this week are all named with the welcome return of James Cronin in the match-day 23 after rehabbing an ankle ligament injury sustained against Leinster in December.
The other change to the front five sees Mark Chisholm makes way for Donnacha Ryan this week with the Ireland international joining fellow Tipperary-lock Dave Foley in the second row.
The backrow of Billy Holland, Tommy O'Donnell and Captain CJ Stander remains in situ.
With no changes in the back-line Conor Murray and Ian Keatley link up once again in the half-backs with the Rory Scannell and Francis Saili pairing in midfield and a back three of Ronan O'Mahony, Keith Earls and Simon Zebo.
The Munster fullback went on to share the honours of Munster's leading try scorer last weekend, equalling Anthony Horgan's tally of 41 tries.
Munster team and replacements to face Treviso:
(15-9): Simon Zebo, Keith Earls, Francis Saili, Rory Scannell, Ronan O'Mahony, Ian Keatley, Conor Murray.
(1-8): Dave Kilcoyne, Mike Sherry, John Ryan, Dave Foley, Donnacha Ryan, Billy Holland, Tommy O'Donnell, CJ Stander (capt).
Replacements (16-23): Niall Scannell, James Cronin, Mario Sagario, Mark Chisholm, Robin Copeland, Jack O'Donoghue, Tomás O'Leary, Gerhard van den Heever.