The 68-year-old is the first woman nominated by a major political party
Hillary Clinton has been officially nominated as the Democratic candidate for the White House - as her husband Bill gave a highly personal speech endorsing her candidacy.
The 68-year-old becomes the first woman to be nominated as a candidate by one of the two major US parties.
Once again there were chants of "Bernie, Bernie" from within the Democratic National Convention Hall in Philadelphia as her former rival Bernie Sanders rose to his feet to admit defeat.
He told delegates: "I move that the convention suspend the procedural rules. I move that all votes cast be reflected in the official record and I move that Hillary Clinton is the democratic candidate for President of the United States."
While Mr Sanders' brother, Larry, tearfully cast his vote "with enormous pride."
The nomination had been a foregone conclusion but Mr Sanders expedited the process in the interests of "unity".
It follows anger from Sanders supporters at both Mrs Clinton's win and embarrassing leaked emails that suggest party insiders tried to stop their man claiming the nomination.
Some protested outside by placing tape over their mouths - suggesting they have been silenced.
The party has at least avoided the rancour seen last week at the Republican Convention when former hopeful Ted Cruz criticised the winning nominee Donald Trump.
When former President Bill Clinton took to the stage to provide a highly personal insight into their lifetime together, thousands in the hall cheered and waved placards saying "change maker".
After describing how he first spotted her at university and asked her to go for a walk, and later proposed, he reeled off her achievements.
He said: "She is still the best darn change maker I have ever known."
Shortly after Bill finished speaking, a video message was played to the hall of Mrs Clinton thanking supporters.
She said: "What an incredible honour you have given me. I can't believe we just put the biggest crack in that glass ceiling yet."
We just put the biggest crack in that glass ceiling yet.” —Hillary https://t.co/mYkaLIv861— Hillary Clinton (@HillaryClinton) July 27, 2016
Among others who spoke in support of Mrs Clinton was the mother of shot dead youngster Trayvon Martin, who is campaigning for an end to gun violence.
Sybrina Fulton said: "Hillary Clinton has the compassion and understanding to support grieving mothers. She has the courage to lead the fight for common sense gun legislation. This isn't about being politically correct. This is about saving our children."
On Monday, First Lady Michelle Obama gave a powerful endorsement which calmed those delegates in the hall who had booed and jeered every mention of Mrs Clinton's name.
Mrs Clinton will not give a full address the convention until Thursday.