This will be CarGurus' first branch outside the US
Some 100 new jobs are to be created by a car shopping website in Dublin.
CarGurus is to establish its European headquarters in Dublin, creating the jobs over the next three years.
The office will be the first branch location for the firm outside the US - and will be a hub for teams that will build country-specific operations in Europe.
CarGurus founder and CEO Langley Steinert said: "It is an exciting time for CarGurus, as we grow our consumer and dealership audiences and expand the reach of our unique car shopping model around the world".
"Dublin gives us access to the exceptional talent we will need to propel our continued success in Europe, and we look forward to joining the vibrant tech community in this great city," he added.
The company was introduced to Ireland through ConnectIreland - the company responsible for delivering the 'Succeed in Ireland' initiative - as part of the Action Plan for Jobs, in association with IDA Ireland.
Martin Shanahan, CEO of IDA Ireland, added: "Ireland continues to attract the best and brightest of today’s technology companies to our shores".
"CarGurus is coming to Ireland for our talent and to be part of the community of tech companies that now call Ireland home. CarGurus base here in Ireland will allow them to continue expanding their company into new European markets".
The company was named a top place to work by the Boston Globe and a "fastest-growing company" by Forbes.
It is currently finalising its office location in Dublin, and intends to be operational by June 2016.