The announcements come from local business PanelDuct and international referral firm BNI
90 jobs have been announced for Mayo.
PanelDuct in Castlebar says it anticipates hiring 80 extra people at its facility over the next three years.
The firm produces flat-pack pre-insulated air ducting technology invented by local man Pat Walsh, and already employs 20 people.
International referral organisation BNI is opening its first office outside the US, also in Castlebar, with the creation of ten jobs.
The business already has 1,200 members and more than 50 groups in Ireland.