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More than €10bn has been wiped off the value of Irish shares since the beginning of 2016.
The ISEQ index has fallen by 15% since January 1st.
The FTSE 100 is trading at a three-year low as international markets remain volatile.
Fears of an economic slowdown in China and the continued oil glut have spooked investors.
Ryanair has become Ireland's largest indigenous company by market capitalisation, passing building material group CRH.
The value of the company rose to €17.3bn at one point - this is the first time that CRH has not topped the ISEQ index since before the financial crash.
Ryanair shares closed at €13.11 - up by almost 3% during the day's trading.
German Finance Minister Wolfgang Schauble said that he is not worried about Deutsche Bank, as bonds and shares in the bank, which is the country's largest, continue to take a hammering.
The bank is reported to be considering buying back several billion euro of debt to shore up its falling share price.
"No, I have no concerns about Deutsche Bank," Mr Schauble said, without offering further detail.
Shares in the bank have dropped by almost 40% so far this year.
There’s growing concern that with historic-low interest rates set to continue bank’s lending margins are coming under increasing pressure; and that some of them may not be as well capitalised to ride out a storm as previously thought -and that a few may even have trouble paying the coupon or dividend on some of their less secured bonds.
A report from property agent DTZ Sherry Fitzgerald has found that occupation levels in the Dublin office market is at the highest level since the peak of Ireland's Tiger years.
It found that average office rents are €592 per sq m - that's almost 90% more than the bottom of the market in 2013.
The Society of Chartered Surveyors Ireland has found that rents in Dublin rose by 24% last year - but it believes that this pace will slow dramatically as prices continue to increase throughout 2016.