He was withdrawn on 16 minutes after a collision with Giorgio Chiellini
Sami Khedira may miss the rest of the European Championships after sustaining a muscle injury during last night's victory over Italy.
Khedira lasted just 16 minutes before making way for Bastian Schweinsteiger after colliding with Italian defender Giorgio Chiellini.
"It was not positive for Khedira to have to go off after 15 minutes," Germany boss Joachim Low told reporters after the game.
"He has muscular problems in his thigh. I am not sure it will be working out for Thursday."
The Juventus midfielder is expected to undergo a scan to assess the extent of the injury.
"It was clear we would need [substitute] Bastian Schweinsteiger over the course of the tournament. He did well, he worked hard and it was important to have his experience on the pitch.
"You need different players in such a tournament, it is not unusual for players to pick up injuries or suspensions. Mats Hummels is suspended for the next game."