Members of the public are being asked to stay away from Cork University Hospital after a recent increase in cases of the winter vomiting bug.
In a statement the HSE has asked people to minimise their visits, either to receive treatment at the emergency department or to see patients.
It says measures to control the outbreak have been implemented within the hospital.
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Meanwhile, the emergency department continues to be extremely busy. From Friday until Sunday, 502 patients presented to the ED, of which 162 patient required inpatient admission.