The Taoiseach Enda Kenny is to travel to Canada next month.
The Government has confirmed he will also meet with the Canadian Prime Minister, Justin Trudeau.
It is expected Mr Kenny will be in Canada for two days in early May.
Discussions between the two leaders will include bilateral relations covering economy and trade and Diaspora matters.
EU-Canada affairs, including the Comprehensive Economic Trade Agreement (CETA) and current key international topics such as UN issues, will also be discussed.
While in Toronto, the Taoiseach will meet with representatives of Enterprise Ireland, Tourism Ireland and the Ireland Chamber of Commerce.
Bilateral merchandise trade between Ireland and Canada reached CAD$2.2bn (€1.47bn) in 2015, according to the Ireland-Canada Chamber of Commerce.
Chemical products, including pharmaceuticals, constituted the largest import and export categories between us.
In 2015, Irish export trade with Canada reached CAD$1.7bn (€1.14bn) - with 70% of the exports comprised pharmaceuticals, 10% whiskey, 7% medical devices and the remaining a mix of goods.