The men are known to gardaí and are reportedly linked to the Kinahan group
Gardaí are believed to have intercepted another feud-related shooting between the Kinahan and Hutch gangs.
Two men aged in their 30s are being held at separate Dublin garda stations following their arrests yesterday.
Members of the Emergency Response Unit and Drugs and Organised Crime Bureau stopped a car on the Naas Dual carriageway yesterday afternoon where a firearm and ammunition were recovered.
A man was arrested.
A second car was stopped on the Long Mile Road in Dublin and the driver was arrested there too.
The men who are known to gardaí are reported to be linked to the Kinahan crime group.
Since the Regency Hotel shooting in Dublin, gardaí have increased armed patrols and surveillance on known gang members.
Yesterday's interception is seen as a major step in preventing more deaths in the ongoing feud between the Hutch and Kinahan gangs - which has so far claimed a number of lives.
The men can be held for up to seven days in custody.